MBZUAI researchers presented DEFUSE-MS at MICCAI 2025, a novel AI system for analyzing changes in MRI scans of multiple sclerosis (MS) patients. DEFUSE-MS uses a deformation field-guided spatiotemporal graph-based framework to identify new lesions by reasoning about how the brain has changed. The model constructs graphs of small regions within baseline and follow-up MRIs, linking them across time with edges enriched with learned embeddings of the deformation field. Why it matters: DEFUSE-MS reframes the task from simple "spot the difference" to understanding structural changes, potentially improving the speed and accuracy of MS diagnosis and treatment monitoring.
The National Multiple Sclerosis Society has awarded funding to four research projects aimed at advancing multiple sclerosis research within the UAE. This initiative marks the third cycle of their Research Grant Programme. The funding supports local scientists and institutions in conducting studies related to the neurological disorder. Why it matters: This commitment strengthens the UAE's capacity in medical research, fostering local scientific innovation and addressing critical health challenges in the region.
KAUST professor Pierre Magistretti has been elected to the Norwegian Academy of Science and Letters. His election recognizes his contributions to neuroscience, specifically his work on lactate's role in brain function. Magistretti's research focuses on the lactate shuttle system and how neurons and glial cells cooperate to meet energy demands. Why it matters: This honor highlights KAUST's contribution to international neuroscience and can foster further collaboration in the field.
MBZUAI researchers led by Dr. Mohammad Yaqub are developing AI algorithms for real-time medical diagnoses, including tools for multiple sclerosis and congenital heart disease. The team developed ScanNav, an AI fetal anomaly assessment system licensed by GE Healthcare for Voluson SWIFT ultrasound machines. ScanNav assists doctors during anomaly scans after 20 weeks of gestation to check for conditions like heart issues and spina bifida. Why it matters: This research has the potential to significantly improve the speed and accuracy of medical diagnoses in the UAE and beyond, addressing critical gaps in healthcare.
Dr. Yves Agid from the ICM Paris Institute of Translational Neuroscience lectured at KAUST's 2018 Winter Enrichment Program about the role of glial cells in brain function and behavior. He highlighted that glial cells, often overlooked in research, are crucial for neural synchronization and overall intelligence. Dysfunction of glial cells can induce pathologies like Alzheimer's and Parkinson's disease. Why it matters: The lecture underscored the importance of studying glial cells in addition to neurons for understanding and treating neurodegenerative disorders, which could influence future research directions at KAUST and in the region.
MBZUAI valedictorian Salma Hassan developed a multimodal graph learning approach for early dementia diagnosis and prognosis. Her master's thesis focused on differential diagnosis to identify specific dementia subtypes and predicting cognitive decline in preclinical patients. The AI model leverages brain imaging, genetics, and clinical records to improve diagnostic accuracy. Why it matters: This research can improve early detection and resource allocation for dementia management, especially in developing countries.
KAUST and the King Salman Center for Disability Research (KSCDR) have signed an MoU to collaborate on the diagnosis, management, and treatment of disabilities affecting Saudi citizens and residents. The partnership will focus on neurodevelopmental conditions, learning disabilities, visual impairments, speech disorders, and mobility impairments. KAUST's Center of Excellence for Smart Health, launched on July 1, will be a key component, leveraging its supercomputing resources and genome sequencing capabilities. Why it matters: This partnership aims to address the increasing prevalence of chronic diseases and disabilities in Saudi Arabia, aligning with national research priorities and improving the quality of life for people with disabilities.